Who can participate? 

• Adults aged 18 and above diagnosed with atopic dermatitis (eczema) may participate. 

Inclusion Criteria 

• Diagnosis of moderate-to-severe atopic dermatitis (AD) present for at least a year 
• AD involvement on 10% or more of your body surface area (BSA)* 
• • History of inadequate response to treatment with topical medications, or medical determination that topical therapies are inadvisable. 

*1% of your body surface area is roughly equal to the palm of your hand (no wrists or fingers)

What Are The Benefits? 

• No cost to participate or receive study treatment 
• Regular visits with study doctors who specialize in treating AD (22 study visits) 
• Will receive either an investigative drug or a placebo – after week 16 until week 52 all participants receive APG777 

How long will the study last? 

• Approximately 2 years 

Note: participants must apply an over-the-counter emollient/moisturizer of their choice for the duration of the study.