Hyaluronidase Quick Facts

Treatment type: Injectable enzyme

Best for: Filler correction or refinement

Downtime: Minimal, mild swelling or bruising possible

Results: Noticeable within hours to days

Performed by: Board-certified dermatologist

Hyaluronidase is an injectable enzyme that breaks down hyaluronic acid (HA) — the substance used in most dermal fillers. At FACET Dermatology, we use hyaluronidase to correct complications such as overfilled areas, asymmetry, or vascular occlusion, and to refine facial contour for a more natural look. Treatment is quick, highly effective, and always performed by a board-certified dermatologist for safety and precision.

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What Is Hyaluronidase?

Hyaluronidase is an enzyme that breaks down hyaluronic acid (HA), the primary ingredient in most dermal fillers. In aesthetics, it is used both as a corrective tool and as a way to restore natural proportions when filler has created heaviness or an unnatural look. Hyaluronidase works quickly and effectively, offering patients peace of mind if they are unhappy with their filler results or require urgent correction.

How Hyaluronidase works

Hyaluronidase is injected directly into the treatment area, where it breaks down HA-based filler. Results are often visible within hours, with continued improvement over several days. Treatment begins with a consultation to determine the best approach, and topical or injectable anesthesia can be used to ensure comfort. In some cases, follow-up sessions may be recommended to achieve the desired level of refinement.

What Does Hyaluronidase Treat?

Hyaluronidase is best suited for dissolving unwanted filler or refining facial contours. It is also used in urgent cases where filler has been misplaced or caused complications.

Concerns treated with hyaluronidase include:

  • Overfilled or heavy areas
  • Asymmetry from filler
  • Lumps or nodules
  • Tyndall effect (bluish tint under the skin)
  • Safety issues such as vascular occlusion
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SEE HOW HYALURONIDASE CAN RESTORE NATURAL BALANCE AND CORRECT FILLER ISSUES

Restore Confidence. Refine Your Look.

Whether correcting a complication or softening an overfilled area, hyaluronidase works quickly to dissolve unwanted filler and restore balance. The result is a more natural, refreshed appearance that aligns with your unique features.

Want to safely refine or correct your filler results?

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Frequently Asked Questions

Is hyaluronidase safe?

Yes. When performed by a board-certified dermatologist, hyaluronidase is very safe. Side effects such as swelling, bruising, or temporary tenderness are possible but typically mild.

How quickly does it work?

Hyaluronidase begins working almost immediately, with visible improvements often within hours. Full results are usually seen within a few days.

Will it remove all of my filler?

The enzyme breaks down HA filler in the treated area. Depending on your goals, your provider can adjust the amount used for complete correction or subtle refinement.

Can I get filler again after hyaluronidase?

Yes. Once the area has healed, new filler can be placed strategically to achieve natural, balanced results.

Do I need more than one treatment?

Most patients achieve their goals with one session, but additional treatments may be recommended if further correction is needed.

What if my filler was done at another clinic?

We can dissolve filler placed elsewhere, but this is carefully assessed on a case-by-case basis to prioritize safety and patient outcomes.