PRF Quick Facts

Treatment type: Injectable, autologous (from your own blood)

Best for: Skin rejuvenation, under-eye hollows, scarring, hair restoration

Downtime: 1–2 days of mild redness or swelling

Sessions: 3–4 treatments spaced 4–6 weeks apart

Results: Gradual improvement over months, lasting 6–12+ months

Platelet-Rich Fibrin (PRF) is the next evolution in regenerative aesthetics, offering more potent and longer-lasting results than PRP.

By using your body’s own platelets, white blood cells, and growth factors — all suspended in a natural fibrin matrix — PRF stimulates collagen, tissue repair, and regeneration for visible, natural improvements to skin, hair, and under-eye hollows. At FACET Dermatology, your PRF treatments are always performed by a board-certified dermatologist for safe, tailored results.

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What Is PRF?

PRF, or Platelet-Rich Fibrin, is a regenerative treatment that uses your body’s own healing factors to stimulate collagen production and repair damaged tissue. Unlike PRP, which is processed with anticoagulants and releases growth factors quickly, PRF is spun at a lower speed, creating a fibrin scaffold that allows for the slow, sustained release of growth factors. This makes it a more advanced and effective option for skin, hair, and under-eye rejuvenation.

How it works

A small amount of your blood is drawn and spun in a specialized centrifuge. This process isolates the PRF, which is then applied or injected into the treatment area. Once introduced, the PRF gradually releases growth factors that stimulate collagen, elastin, and tissue repair. Because PRF is 100% natural and biocompatible, there are no additives or chemicals involved, making it one of the safest regenerative treatments available.

What Does PRF Treat?

PRF is a versatile treatment that can rejuvenate the skin, restore volume in delicate areas like the under eyes, support hair growth, and remodel scarring. Results are subtle and natural, making PRF an excellent option for patients looking for regenerative, non-surgical improvements.

  • Concerns treated with PRF include:
  • Fine lines and wrinkles
  • Under-eye hollows and dark circles
  • Acne and surgical scars
  • Sun-damaged or aging skin
  • Thinning hair or androgenetic alopecia

For patients primarily seeking skin tightening, Ultherapy may be a better fit. If volume restoration is the main concern, consider Dermal Fillers or Biostimulatory Fillers as complementary options.

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PRF VS PRP:

What's the Difference?

Features

PRP (Platelet-Rich Plasma)

PRF (Platelet-Rich Fibrin)

Processing

Spun at high speed, uses anticoagulants

Spun at lower speed, no additives

Growth Factor Release

Removes raised portion flush with skin surface

Removes entire lesion, including root

Structure

Best for benign raised lesions (e.g., moles, keratoses, skin tags)

Recommended for suspicious, cancerous, or deep lesions

Longevity

Faster healing (1–2 weeks) with minimal downtime

Slightly longer healing time due to sutures

Results

Lower risk of prominent scarring

Higher risk of scarring but ensures complete removal

NATURAL REGENERATION FOR SKIN, HAIR, AND SCARS

Subtle, Lasting Improvements That Build Over Time

With PRF, results develop gradually as your body produces new collagen and tissue regeneration occurs. This means smoother skin, brighter eyes, denser hair, and a refreshed, more youthful look that feels completely natural.

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Frequently Asked Questions

How is PRF different from PRP?

PRF is processed without anticoagulants and spun at a lower speed, creating a fibrin matrix that releases growth factors slowly and continuously. This makes it more powerful and longer-lasting than PRP.

Is PRF safe?

Yes. PRF is autologous — meaning it comes entirely from your own blood — so it is biocompatible, chemical-free, and extremely safe when performed by a trained dermatologist.

How many PRF treatments will I need?

Most patients benefit from 3–4 sessions spaced 4–6 weeks apart, followed by maintenance sessions every 6–12 months depending on goals.

What is the downtime after PRF?

Downtime is minimal. You may experience redness or swelling for 1–2 days. Most patients return to daily activities right away.

Can PRF treat under-eye hollows?

Yes. PRF is commonly used in the tear trough area to improve dark circles, volume loss, and crepiness, offering a natural alternative to fillers.

Can PRF be combined with other treatments?

Absolutely. PRF pairs well with microneedling, lasers, or dermal fillers to enhance results. Your provider will customize the best combination for your needs.

When will I see results?

You’ll notice gradual improvement over several weeks, with full results developing over 3–6 months as collagen production builds.