Vitiligo Quick Facts

Concern: Loss of skin pigment in patches due to autoimmune activity

Common Areas: Face, hands, arms, feet, and around body openings

Causes: Autoimmune, genetic, or environmental factors that target pigment-producing cells (melanocytes)

Treatment Options: Light therapy, topical or oral medications, prescription skincare, clinical trials

Downtime: None

Results: Gradual restoration of pigment and reduction of contrast between affected and surrounding skin

Understanding Vitiligo

Vitiligo is an autoimmune skin condition that causes loss of pigment (melanin), resulting in white or light patches on the skin. It occurs when the immune system attacks melanocytes — the cells responsible for producing pigment — and can appear on any area of the body.

Although vitiligo is harmless, it can have significant emotional and psychological effects, particularly when it affects visible areas such as the face, hands, or neck. While there is no cure, modern dermatology offers effective treatments that can help slow progression and restore pigment.

At FACET Dermatology, our dermatologists combine clinical expertise with advanced technology to personalize your care, from light therapy and topical treatments to clinical trials exploring breakthrough therapies for vitiligo.

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Treatment & Recommended Services

Successful vitiligo treatment focuses on re-stimulating pigment production, reducing inflammation, and balancing immune activity. Your dermatologist will assess your skin type, pattern of depigmentation, and medical history to design an individualized plan.

Your treatment plan may include:

  • Phototherapy (Light Therapy): Narrowband UVB therapy to stimulate melanocyte activity and even out skin tone
  • Topical medications: Such as calcineurin inhibitors or JAK inhibitors to reduce immune inflammation
  • Oral therapies: To help regulate the immune system in widespread or active cases
  • Prescription Skincare Guidance: To support skin health and protect against further pigment loss
  • Clinical Trials: For access to new topical, oral, or biologic therapies currently under investigation

All vitiligo treatments are dermatologist-supervised and tailored for safety, comfort, and long-term results.

Book a consultation to discuss your options and find out if you qualify for one of our ongoing vitiligo clinical trials.

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Vitiligo and Clinical Trials

FACET Dermatology is actively involved in clinical research focused on repigmentation and immune regulation in vitiligo. Through our clinical trials program, eligible patients can access innovative treatments not yet available to the public.

Participation may allow you to:

  • Receive cutting-edge therapies under medical supervision
  • Contribute to the future of pigment restoration research
  • Be closely monitored by our team of board-certified dermatologists and research coordinators

All trials are conducted according to Health Canada-approved safety and ethical standards, ensuring the highest level of patient care.

If you’re interested in exploring advanced treatment options for vitiligo, ask our team about current clinical trials available at FACET Dermatology.

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Frequently Asked Questions

What causes vitiligo?

Vitiligo occurs when the immune system attacks pigment-producing cells in the skin. Genetics, autoimmune activity, and environmental triggers may all play a role.

Is vitiligo curable?

There’s no permanent cure, but modern treatments can restore pigment, slow progression, and reduce contrast between affected and normal skin.

Are clinical trials safe?

Yes. All clinical trials at FACET Dermatology follow Health Canada guidelines and are overseen by our dermatologists and research specialists.

Can vitiligo come back after treatment?

Some areas may lose pigment again over time. Ongoing management, sun protection, and early intervention help maintain results.

Does light therapy work for everyone?

Light therapy is one of the most effective treatments for vitiligo, but response varies. Your dermatologist will determine if it’s right for your skin type and condition.

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